China (Mainland)
Capecitabine CAS NO.154361-50-9
- Min.Order: 10 Gram
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- Product Details
Keywords
- 99% Capecitabine
- supply 99% Capecitabine
- Capecitabine
Quick Details
- ProName: Capecitabine
- CasNo: 154361-50-9
- Appearance: crystal or powder
- Application: antitumor drug. colon cancer adjuvant ...
- DeliveryTime: within 1bdays after your payment
- PackAge: aluminiul foil bag or as your request
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Storage: cool.sealed place
- Transportation: by courier or as your request
- LimitNum: 10 Gram
Superiority
English name: Capecitabine
used in the treatment of metastatic breast and colorectal cancers
(skype:pamelasurvivor)
Details
1.Introduction of Capecitabine
The Capecitabine, with the CAS registry number 154361-50-9, is also known as N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine. It belongs to the product categories of Active Pharmaceutical Ingredients; Antineoplastic; Bases & Related Reagents; Intermediates & Fine Chemicals; Nucleotides; Pharmaceuticals; Antineoplastic drug, 5-FU analog; Anti-cancer. This chemical's molecular formula is C15H22FN3O6 and molecular weight is 359.35. What's more, its systematic name is 5'-Deoxy-5-fluoro-N-
[(pentyloxy)carbonyl]cytidine. Its classification codes are: (1)Antimetabolites; (2)Antimetabolites, Antineoplastic; (3)Antineoplastic; (4)Antineoplastic agents; (5)Noxae. This chemical is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug of doxifluridine and an antineoplastic agent , that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
2.Physical properties of Capecitabine
(1)ACD/LogP: 1.042; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.76; (4)ACD/LogD (pH 7.4): -0.60; (5)ACD/BCF (pH 5.5): 1.89; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 45.62; (8)ACD/KOC (pH 7.4): 2.02; (9)#H bond acceptors: 9; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 8; (12)Polar Surface Area: 120.69 2; (13)Index of Refraction: 1.6; (14)Molar Refractivity: 82.327 cm3; (15)Molar Volume: 240.522 cm3; (16)Polarizability: 32.637 10-24cm3; (17)Surface Tension: 51.3009986877441 dyne/cm; (18)Density: 1.494 g/cm3.
3.Structure of Capecitabine
(1)SMILES: FC=1\C(=N/C(=O)N(C=1)[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)C)\N
C(=O)OCCCCC
(2)Std. InChI: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-
11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
(3)Std. InChIKey: GAGWJHPBXLXJQN-UORFTKCHSA-N
4.Pharmacodynamics of Capecitabine
it is a fluoropyrimidine
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